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GPR142
Identifiers
Aliases	GPR142, PGR2, G protein-coupled receptor 142, GPRg1b
External IDs	OMIM: 609046; MGI: 2668437; HomoloGene: 18770; GeneCards: GPR142; OMA:GPR142 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.1 Start 74,367,458 bp End 74,372,600 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E2 Start 114,689,750 bp End 114,697,571 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans spleen duodenum granulocyte lymph node gastric mucosa left uterine tube right lobe of thyroid gland appendix canal of the cervix Top expressed in islet of Langerhans embryo CA3 field cochlea pharynx cartilage tissue neck habenula peripheral nervous system medial habenular nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane cell junction membrane plasma membrane cytosol Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 350383 217302 Ensembl ENSG00000257008 ENSMUSG00000034677 UniProt Q7Z601 Q7TQN9 RefSeq (mRNA) NM_181790 NM_001331076 NM_001331077 NM_181749 NM_001346772 NM_001379097 RefSeq (protein) NP_001318005 NP_001318006 NP_861455 NP_001333701 NP_861414 NP_001366026 Location (UCSC) Chr 17: 74.37 – 74.37 Mb Chr 11: 114.69 – 114.7 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 142 is a protein that in humans is encoded by the GPR142 gene.

GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).

References

1. ^ GRCh38: Ensembl release 89: ENSG00000257008 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000034677 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi:10.1016/S0014-5793(03)01196-7. PMID 14623098. S2CID 11563502.
6. ^ "Entrez Gene: GPR142 G protein-coupled receptor 142".

Further reading

• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
• Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.

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