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Sulbentine

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Chemical compound Pharmaceutical compound
Sulbentine
Clinical data
ATC code
Identifiers
IUPAC name
  • 3,5-bis(phenylmethyl)-1,3,5-thiadiazinane-2-thione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.005.907 Edit this at Wikidata
Chemical and physical data
FormulaC17H18N2S2
Molar mass314.46 g·mol
3D model (JSmol)
SMILES
  • c1ccc(cc1)CN2CN(C(=S)SC2)Cc3ccccc3
InChI
  • InChI=1S/C17H18N2S2/c20-17-19(12-16-9-5-2-6-10-16)13-18(14-21-17)11-15-7-3-1-4-8-15/h1-10H,11-14H2
  • Key:QFVAWNPSRQWSDU-UHFFFAOYSA-N
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Sulbentine (or dibenzthione) is an antifungal.

References

  1. Hänel H, Raether W, Dittmar W (1988). "Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics". Annals of the New York Academy of Sciences. 544 (1): 329–37. Bibcode:1988NYASA.544..329H. doi:10.1111/j.1749-6632.1988.tb40417.x. PMID 3214073. S2CID 13183316.
Antifungals (D01 and J02)
Wall/
membrane
Ergosterol
inhibitors
Azoles (lanosterol 14α-
demethylase inhibitors)
Imidazoles
  • Systemic: ketoconazole
Triazoles
Thiazoles
Polyene antimycotics
(ergosterol binding)
Squalene monooxygenase
inhibitors
Allylamines
Benzylamines
Others
β-glucan synthase
inhibitors
Intracellular
Pyrimidine analogues/
thymidylate synthase inhibitors
Mitotic inhibitors
Aminoacyl tRNA synthetase inhibitors
Others
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