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Luliconazole

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Chemical compound Pharmaceutical compound
Luliconazole
Clinical data
Trade namesLuzu, Luzarn, Lulicon, LULY, Zyluli,Luris
Routes of
administration
Topical
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding>99%
Identifiers
IUPAC name
  • (2E)-(1H-imidazol-1-yl)acetonitrile
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H9Cl2N3S2
Molar mass354.27 g·mol
3D model (JSmol)
SMILES
  • C1(S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
InChI
  • InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
  • Key:YTAOBBFIOAEMLL-REQDGWNSSA-N

Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum, and Epidermophyton floccosum.

References

  1. ^ "LUZU (luliconazole) Cream, 1%. Full Prescribing Information" (PDF). Valeant Pharmaceuticals North America LLC. Retrieved 1 October 2015.
  2. Gupta AK, Daigle D (2016). "A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections". Infection and Drug Resistance. 9: 1–6. doi:10.2147/IDR.S61998. PMC 4723097. PMID 26848272.
  3. "FDA approves luliconazole for tinea pedis". November 19, 2013. Archived from the original on 16 January 2014. Retrieved 14 January 2014.

External links

Antifungals (D01 and J02)
Wall/
membrane
Ergosterol
inhibitors
Azoles (lanosterol 14α-
demethylase
inhibitors)
Imidazoles
  • Systemic: ketoconazole
Triazoles
Thiazoles
Polyene antimycotics
(ergosterol binding)
Squalene monooxygenase
inhibitors
Allylamines
Benzylamines
Others
β-glucan synthase
inhibitors
Intracellular
Pyrimidine analogues/
thymidylate synthase inhibitors
Mitotic inhibitors
Aminoacyl tRNA synthetase inhibitors
Others
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