Croconazole - Misplaced Pages

Chemical compound

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Pharmaceutical compound

Croconazole
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
ATC code	None
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 1-(1-{2-phenyl}ethenyl)-1H-imidazole
CAS Number	77175-51-0
PubChem CID	2880
ChemSpider	2777
UNII	446254H55G
KEGG	D07752
ChEMBL	ChEMBL27289
CompTox Dashboard (EPA)	DTXSID6058475
Chemical and physical data
Formula	C₁₈H₁₅ClN₂O
Molar mass	310.78 g·mol
3D model (JSmol)	Interactive image
SMILES Clc1cccc(c1)COc3c(\C(=C)n2ccnc2)cccc3

Croconazole (INN) is an imidazole antifungal.

References

Pfaller MA (2010). "Chapter 143: Croconazole". In Turner A (ed.). Logan Turner's Diseases of the Nose, Throat and Ear. Kucers' the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs. Vol. 2 (6th ed.). Boca Raton, Florida: CRC Press. p. 1903. ISBN 978-0-340-92767-0.

Wall/
membrane

Ergosterol
inhibitors

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic: flucytosine
Mitotic inhibitors	Systemic: griseofulvin
Aminoacyl tRNA synthetase inhibitors	Topical: tavaborole

Others

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