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Dimazole

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Chemical compound Pharmaceutical compound

Dimazole
Clinical data

ATC code	D01AE17 (WHO)
Identifiers
IUPAC name -dimethyl-amine
CAS Number	95-27-2
PubChem CID	8708
ChemSpider	8384
UNII	2KL01R8ZV1
CompTox Dashboard (EPA)	DTXSID1046182
ECHA InfoCard	100.002.188
Chemical and physical data
Formula	C₁₅H₂₃N₃OS
Molar mass	293.43 g·mol
3D model (JSmol)	Interactive image
Melting point	195 to 204 °C (383 to 399 °F)
SMILES CCN(CC)CCOc1ccc2c(c1)sc(n2)N(C)C
InChI InChI=1S/C15H23N3OS/c1-5-18(6-2)9-10-19-12-7-8-13-14(11-12)20-15(16-13)17(3)4/h7-8,11H,5-6,9-10H2,1-4H3 Key:WGMYEOIMVYADRJ-UHFFFAOYSA-N
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Dimazole (or diamthazole) is an antifungal compound.

References

Drugs.com: diamthazole dihydrochloride

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Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles (lanosterol 14α-
demethylase inhibitors)

Systemic: ketoconazole

Unknown: albaconazole
ravuconazole

Topical: abafungin

Polyene antimycotics
(ergosterol binding)

Topical: hamycin
natamycin
nystatin
Systemic: amphotericin B, hamycin

Squalene monooxygenase
inhibitors

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical: butenafine

Others

Topical: amorolfine

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic: flucytosine
Mitotic inhibitors	Systemic: griseofulvin
Aminoacyl tRNA synthetase inhibitors	Topical: tavaborole

Others

WHO-EM
Withdrawn from market
Clinical trials:
- Phase III
- Never to phase III

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