Cytochrome P450, family 15, also known as CYP15, is an animal cytochrome P450 family found in insect genome, involved in juvenile hormone biosynthesis. The first gene identified in this family is the DpCYP15A1 from the Diploptera punctata (Pacific beetle cockroach), encodes an epoxidase of methyl farnesoate, a precursor of juvenile hormone, alone with its ortholog TcCYP15A1 in Tribolium castaneum (red flour beetle).
References
- Nelson, DR (November 1998). "Metazoan cytochrome P450 evolution". Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 121 (1–3): 15–22. doi:10.1016/s0742-8413(98)10027-0. PMID 9972448.
- Daimon, T; Shinoda, T (January 2013). "Function, diversity, and application of insect juvenile hormone epoxidases (CYP15)". Biotechnology and Applied Biochemistry. 60 (1): 82–91. doi:10.1002/bab.1058. PMID 23586995. S2CID 25181420.
- Minakuchi, C; Ishii, F; Washidu, Y; Ichikawa, A; Tanaka, T; Miura, K; Shinoda, T (September 2015). "Expressional and functional analysis of CYP15A1, a juvenile hormone epoxidase, in the red flour beetle Tribolium castaneum". Journal of Insect Physiology. 80: 61–70. doi:10.1016/j.jinsphys.2015.04.008. PMID 25921675.
Cytochromes, oxygenases: cytochrome P450 (Most belong to EC 1.14) | |
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CYP1 | |
CYP2 | |
CYP3 (CYP3A) | |
CYP4 | |
CYP5-20 | |
CYP21-49 | |
CYP51-69 | |
CYP71-99 | |
CYP101-281 | |
CYP301-499 | |
CYP501-699 | |
CYP701-999 |
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