| cytochrome P450, family 11, subfamily b, polypeptide 3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | Rattus norvegicus | ||||||
| Symbol | CYP11B3 | ||||||
| Entrez | 353498 | ||||||
| HomoloGene | 106948 | ||||||
| RefSeq (mRNA) | NM_181824.1 | ||||||
| RefSeq (Prot) | NP_861545.1 | ||||||
| UniProt | P30100 | ||||||
| Other data | |||||||
| EC number | 1.14.15.4 | ||||||
| Chromosome | 7: 116.16 - 116.26 Mb | ||||||
| |||||||
The Cyp11b3 is a rat gene encoding a CYP450 enzyme, which is mainly expressed in neonatal rat adrenals, and also expressed in a small amount in other organs of adult rats, this enzyme mainly catalyzing 11-Deoxycorticosterone (DOC) to 18-Hydroxy-11-deoxycorticosterone (18-OH-DOC). Cyp11b3 gene is also located at Chromosome 7q34, next to rat CYP11B1 and CYP11B2.
References
- Zhou MY, Gomez-Sanchez EP, Foecking MF, Gomez-Sanchez CE (October 1995). "Cloning and expression of the rat adrenal cytochrome P-450 11B3 (CYP11B3) enzyme cDNA: preferential 18-hydroxylation over 11 beta-hydroxylation of DOC". Molecular and Cellular Endocrinology. 114 (1–2): 137–45. doi:10.1016/0303-7207(95)03653-o. PMID 8674838. S2CID 53252461.
| Cytochromes, oxygenases: cytochrome P450 (Most belong to EC 1.14) | |
|---|---|
| CYP1 | |
| CYP2 | |
| CYP3 (CYP3A) | |
| CYP4 | |
| CYP5-20 | |
| CYP21-49 | |
| CYP51-69 | |
| CYP71-99 | |
| CYP101-281 | |
| CYP301-499 | |
| CYP501-699 | |
| CYP701-999 | |