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CP 42,096

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Cannabinoid agonist drug Pharmaceutical compound
CP 42,096
Identifiers
IUPAC name
  • (6aR,9R,10aR)-6,6-dimethyl-3-(5-phenylpentan-2-yloxy)-6a,7,8,9,10,10a-hexahydrobenzochromene-1,9-diol
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC26H34O4
Molar mass410.554 g·mol
3D model (JSmol)
SMILES
  • CC(CCCC1=CC=CC=C1)OC2=CC(=C34C(CC4C(OC3=C2)(C)C)O)O
InChI
  • InChI=1S/C26H34O4/c1-17(8-7-11-18-9-5-4-6-10-18)29-20-15-23(28)25-21-14-19(27)12-13-22(21)26(2,3)30-24(25)16-20/h4-6,9-10,15-17,19,21-22,27-28H,7-8,11-14H2,1-3H3/t17?,19-,21-,22-/m1/s1
  • Key:YIUCAHIOICYGOA-WNBFYKTCSA-N

CP 42,096 is an analgesic drug which acts as a cannabinoid agonist. It was developed by Pfizer in the 1980s as part of the research that led to the development of levonantradol, and is more potent than THC but less potent than newer compounds such as CP 55,244.

See also

References

  1. Howlett AC, Johnson MR, Melvin LS, Milne GM (March 1988). "Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model". Molecular Pharmacology. 33 (3): 297–302. PMID 3352594.
  2. Prescott WR, Martin BR (1990). "The evaluation of synthetic cannabimimetic congeners for discriminative stimulus and cataleptogenic effects in rats". NIDA Research Monograph. 105: 421. OCLC 7457082. PMID 1652087.
  3. Koe BK (1999). "Levonantradol". In Nahas GG, Sutin KM, Harvey D, Agurell S, Pace N, Cancro R (eds.). Marihuana and Medicine. Totowa, NJ: Humana Press. pp. 553–560. doi:10.1007/978-1-59259-710-9_53. ISBN 978-1-4757-5717-0.
  4. Koe BK, Milne GM, Weissman A, Johnson MR, Melvin LS (February 1985). "Enhancement of brain flunitrazepam binding and analgesic activity of synthetic cannabimimetics". European Journal of Pharmacology. 109 (2): 201–12. doi:10.1016/0014-2999(85)90421-2. PMID 2986995.
  5. "Hexahydrocannabinol (HHC) and related substances" (PDF). European Monitoring Centre for Drugs and Drug Addiction. 2023.
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