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OR4D1

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Protein-coding gene in the species Homo sapiens
OR4D1
Identifiers
AliasesOR4D1, OR17-23, OR4D3, OR4D4P, TPCR16, olfactory receptor family 4 subfamily D member 1
External IDsMGI: 3030298; HomoloGene: 44975; GeneCards: OR4D1; OMA:OR4D1 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)
Chromosome 17 (human)Genomic location for OR4D1Genomic location for OR4D1
Band17q22Start58,148,384 bp
End58,159,585 bp
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)
Chromosome 11 (mouse)Genomic location for OR4D1Genomic location for OR4D1
Band11|11 CStart87,804,094 bp
End87,811,793 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • lymph node

  • blood

  • cecum

  • pharynx

  • appendix

  • spleen

  • tonsil
Top expressed in
  • embryo

  • secondary oocyte

  • Hypothalamus

  • primary visual cortex

  • superior frontal gyrus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26689

258407

Ensembl

ENSG00000141194

ENSMUSG00000060787

UniProt

Q15615

Q5SW48

RefSeq (mRNA)

NM_012374
NM_001386095

NM_146412

RefSeq (protein)

NP_036506

NP_666524

Location (UCSC)Chr 17: 58.15 – 58.16 MbChr 11: 87.8 – 87.81 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4D1 is a protein that in humans is encoded by the OR4D1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000141194Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000060787Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
  6. ^ "Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


G protein-coupled receptors: olfactory receptors
Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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