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OR10AD1
Identifiers
Aliases	OR10AD1, OR10AD1P, OR12-1, olfactory receptor family 10 subfamily AD member 1
External IDs	MGI: 3030122; HomoloGene: 128379; GeneCards: OR10AD1; OMA:OR10AD1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.11 Start 48,202,339 bp End 48,203,292 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 F1 Start 98,083,894 bp End 98,093,423 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Pituitary Gland granulocyte right uterine tube tonsil anterior pituitary right adrenal cortex Achilles tendon right hemisphere of cerebellum appendix Top expressed in primary oocyte secondary oocyte zygote mandible respiratory epithelium peripheral nervous system nasal epithelium olfactory epithelium ovary cerebellar cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 121275 545140 Ensembl ENSG00000172640 ENSMUSG00000075427 UniProt Q8NGE0 E9Q1P2 RefSeq (mRNA) NM_001004134 NM_001011733 RefSeq (protein) NP_001004134 NP_001011733 Location (UCSC) Chr 12: 48.2 – 48.2 Mb Chr 15: 98.08 – 98.09 Mb PubMed search
Wikidata
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Olfactory receptor 10AD1 is a protein that in humans is encoded by the OR10AD1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

References

1. ^ GRCh38: Ensembl release 89: ENSG00000172640 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000075427 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: OR10AD1 olfactory receptor, family 10, subfamily AD, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR10AD1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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