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Bunaftine

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Revision as of 06:29, 31 August 2011 by BogBot (talk | contribs) (populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Bunaftine
Clinical data
ATC code
Identifiers
IUPAC name
  • N--N-propylnaphthalene-1-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.046.373 Edit this at Wikidata
Chemical and physical data
FormulaC21H30N2O
Molar mass326.476 g/mol g·mol
3D model (JSmol)
SMILES
  • O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12
InChI
  • InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3
  • Key:WWGZXRYELYWJBD-UHFFFAOYSA-N
  (what is this?)  (verify)

Bunaftine is a antiarrhythmic agent. It is classified in class III.

It is also spelled "bunaphtine".

References

  1. Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M (1983). "Intropic effects of several antiarrhythmic drugs". Jpn Heart J. 24 (3): 377–90. PMID 6876382. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. Fenici R, Marchei M, Bellocci F, Zecchi P (1977). "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J. 39 (7): 787–94. doi:10.1136/hrt.39.7.787. PMC 483317. PMID 328029. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. Tamargo J (1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther. 246 (2): 224–36. PMID 7436628. {{cite journal}}: Unknown parameter |month= ignored (help)
Ion channel modulators
Calcium
VDCCsTooltip Voltage-dependent calcium channels
Blockers
Activators
Potassium
VGKCsTooltip Voltage-gated potassium channels
Blockers
Activators
IRKsTooltip Inwardly rectifying potassium channel
Blockers
Activators
KCaTooltip Calcium-activated potassium channel
Blockers
Activators
K2PsTooltip Tandem pore domain potassium channel
Blockers
Activators
Sodium
VGSCsTooltip Voltage-gated sodium channels
Blockers
Activators
ENaCTooltip Epithelial sodium channel
Blockers
Activators
ASICsTooltip Acid-sensing ion channel
Blockers
Chloride
CaCCsTooltip Calcium-activated chloride channel
Blockers
Activators
CFTRTooltip Cystic fibrosis transmembrane conductance regulator
Blockers
Activators
Unsorted
Blockers
Others
TRPsTooltip Transient receptor potential channels
LGICsTooltip Ligand gated ion channels
See also: Receptor/signaling modulators • Transient receptor potential channel modulators
Antiarrhythmic agents (C01B)
Channel blockers
class I
(Na channel blockers)
class Ia (Phase 0→ and Phase 3→)
class Ib (Phase 3←)
class Ic (Phase 0→)
class III
(Phase 3→, K channel blockers)
class IV
(Phase 4→, Ca channel blockers)
Receptor agonists
and antagonists
class II
(Phase 4→, β blockers)
A1 agonist
M2
α receptors
Ion transporters
Na/ K-ATPase


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