Ethadione - Misplaced Pages

Chemical compound Not to be confused with ethanedione or ethenedione. Pharmaceutical compound

Ethadione
Clinical data

ATC code	N03AC03 (WHO)
Identifiers
IUPAC name 3-Ethyl-5,5-dimethyl-1,3-oxazolidine-2,4-dione
CAS Number	520-77-4
PubChem CID	10630
ChemSpider	10184
UNII	I0F8O700BB
KEGG	C17724
ChEMBL	ChEMBL93047
CompTox Dashboard (EPA)	DTXSID90199972
ECHA InfoCard	100.007.544
Chemical and physical data
Formula	C₇H₁₁NO₃
Molar mass	157.169 g·mol
3D model (JSmol)	Interactive image
SMILES O=C1N(C(=O)OC1(C)C)CC
InChI InChI=1S/C7H11NO3/c1-4-8-5(9)7(2,3)11-6(8)10/h4H2,1-3H3 Key:SIGSNYAYBSJATD-UHFFFAOYSA-N
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Ethadione is an anticonvulsant medication in the oxazolidinedione family used mainly to treat seizures.

References

Bergstrand A, Bergstrand CG, Engstrom N, Herrlin KM (October 1962). "Renal histology during treatment with oxazolidine-diones (trimethadione, ethadione, and paramethadione)". Pediatrics. 30 (4): 601–7. doi:10.1542/peds.30.4.601. PMID 13970793. S2CID 7313535.

GABA_AR PAMs	Barbiturates: Barbexaclone Metharbital Methylphenobarbital Pentobarbital Phenobarbital Primidone; Carbamates: Cenobamate Felbamate; Benzodiazepines: Clobazam Clonazepam Clorazepate Diazepam Lorazepam Midazolam Nimetazepam Nitrazepam Temazepam; Others: Bromide (potassium bromide, sodium bromide) Imepitoin Paraldehyde Stiripentol
GABA-T inhibitors	Fatty acids (and related): Valproate Valpromide Valproate pivoxil Vigabatrin
Others	GABAR agonists: Progabide; GAT-1 inhibitors: Tiagabine

Sodium blockers	Hydantoins: Ethotoin Fosphenytoin Mephenytoin Phenytoin; Ureides: Acetylpheneturide Chlorphenacemide Phenacemide Pheneturide; Fatty acids: Valproate Valpromide Valproate pivoxil; Carboxamides: Carbamazepine Eslicarbazepine acetate Oxcarbazepine; Others: Lacosamide Lamotrigine Rufinamide Topiramate Zonisamide
Calcium blockers	Oxazolidinediones: Ethadione Paramethadione Trimethadione; Succinimides: Ethosuximide Mesuximide Phensuximide; Gabapentinoids: Gabapentin Pregabalin; Others: Imepitoin Lamotrigine Topiramate Zonisamide
Potassium openers	Retigabine

Others

CA inhibitors	Sulfonamides: Acetazolamide Ethoxzolamide Sultiame Topiramate Zonisamide
Others	Albutoin Beclamide Brivaracetam Cannabidiol Carisbamate Etiracetam Fenfluramine Ganaxolone Levetiracetam Perampanel

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