Nipigon may refer to:
Places in Thunder Bay District of Ontario, Canada
- Nipigon Township
- Lake Nipigon
- Lake Nipigon (electoral district)
- Nipigon River
- Nipigon Bay, northern-most bay of Lake Superior
- Nipigon Embayment
- Lake Nipigon Indian Reserve
Canadian Navy ships
- HMCS Nipigon (J154), a Bangor-class minesweeper that served in World War II
- HMCS Nipigon (DDH 266), an Annapolis-class destroyer that served during the Cold War
Other uses
- Nipigon (crater), an impact crater on Mars
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