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In molecular biology mir-185 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

See also

• MicroRNA

References

Further reading

• Liu T, Cheng W, Gao Y, Wang H, Liu Z (September 2012). "Microarray analysis of microRNA expression patterns in the semen of infertile men with semen abnormalities". Molecular Medicine Reports. 6 (3): 535–42. doi:10.3892/mmr.2012.967. PMID 22735917.
• Perri R, Nares S, Zhang S, Barros SP, Offenbacher S (January 2012). "MicroRNA modulation in obesity and periodontitis". Journal of Dental Research. 91 (1): 33–8. doi:10.1177/0022034511425045. PMC 3232116. PMID 22043006.
• Zhang Z, Tang H, Wang Z, Zhang B, Liu W, Lu H, Xiao L, Liu X, Wang R, Li X, Wu M, Li G (September 2011). "MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma". Molecular Cancer. 10: 124. doi:10.1186/1476-4598-10-124. PMC 3193026. PMID 21962230.
• Oak SR, Murray L, Herath A, Sleeman M, Anderson I, Joshi AD, Coelho AL, Flaherty KR, Toews GB, Knight D, Martinez FJ, Hogaboam CM (2011). Feghali-Bostwick C (ed.). "A micro RNA processing defect in rapidly progressing idiopathic pulmonary fibrosis". PLOS ONE. 6 (6): e21253. doi:10.1371/journal.pone.0021253. PMC 3119674. PMID 21712985.
• Zheng ZF, Su HF, Zou Y, Peng Z, Wu SX (March 2011). "". Zhonghua Yi Xue Za Zhi. 91 (9): 639–42. PMID 21600139.
• Farazi TA, Horlings HM, Ten Hoeve JJ, Mihailovic A, Halfwerk H, Morozov P, Brown M, Hafner M, Reyal F, van Kouwenhove M, Kreike B, Sie D, Hovestadt V, Wessels LF, van de Vijver MJ, Tuschl T (July 2011). "MicroRNA sequence and expression analysis in breast tumors by deep sequencing". Cancer Research. 71 (13): 4443–53. doi:10.1158/0008-5472.CAN-11-0608. PMC 3129492. PMID 21586611.
• Akçakaya P, Ekelund S, Kolosenko I, Caramuta S, Ozata DM, Xie H, Lindforss U, Olivecrona H, Lui WO (August 2011). "miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer". International Journal of Oncology. 39 (2): 311–8. doi:10.3892/ijo.2011.1043. PMID 21573504.
• Yu F, Cui Y, Zhou X, Zhang X, Han J (2011). "Osteogenic differentiation of human ligament fibroblasts induced by conditioned medium of osteoclast-like cells". BioScience Trends. 5 (2): 46–51. doi:10.5582/bst.2011.v5.2.46. PMID 21572246.
• Greenberg E, Hershkovitz L, Itzhaki O, Hajdu S, Nemlich Y, Ortenberg R, Gefen N, Edry L, Modai S, Keisari Y, Besser MJ, Schachter J, Shomron N, Markel G (April 2011). Gullberg D (ed.). "Regulation of cancer aggressive features in melanoma cells by microRNAs". PLOS ONE. 6 (4): e18936. doi:10.1371/journal.pone.0018936. PMC 3081841. PMID 21541354.
• Östling P, Leivonen SK, Aakula A, Kohonen P, Mäkelä R, Hagman Z, Edsjö A, Kangaspeska S, Edgren H, Nicorici D, Bjartell A, Ceder Y, Perälä M, Kallioniemi O (March 2011). "Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells". Cancer Research. 71 (5): 1956–67. doi:10.1158/0008-5472.CAN-10-2421. PMID 21343391.
• Liu M, Lang N, Chen X, Tang Q, Liu S, Huang J, Zheng Y, Bi F (February 2011). "miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells". Cancer Letters. 301 (2): 151–60. doi:10.1016/j.canlet.2010.11.009. PMID 21186079.
• Ichi S, Costa FF, Bischof JM, Nakazaki H, Shen YW, Boshnjaku V, Sharma S, Mania-Farnell B, McLone DG, Tomita T, Soares MB, Mayanil CS (November 2010). "Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development". The Journal of Biological Chemistry. 285 (47): 36922–32. doi:10.1074/jbc.M110.126714. PMC 2978621. PMID 20833714.
• Yang Y, Li X, Yang Q, Wang X, Zhou Y, Jiang T, Ma Q, Wang YJ (July 2010). "The role of microRNA in human lung squamous cell carcinoma". Cancer Genetics and Cytogenetics. 200 (2): 127–33. doi:10.1016/j.cancergencyto.2010.03.014. PMID 20620595.
• Imam JS, Buddavarapu K, Lee-Chang JS, Ganapathy S, Camosy C, Chen Y, Rao MK (September 2010). "MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers". Oncogene. 29 (35): 4971–9. doi:10.1038/onc.2010.233. PMID 20603620.
• Liu H, Brannon AR, Reddy AR, Alexe G, Seiler MW, Arreola A, Oza JH, Yao M, Juan D, Liou LS, Ganesan S, Levine AJ, Rathmell WK, Bhanot GV (April 2010). "Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma". BMC Systems Biology. 4: 51. doi:10.1186/1752-0509-4-51. PMC 2876063. PMID 20420713.
• Yao Y, Suo AL, Li ZF, Liu LY, Tian T, Ni L, Zhang WG, Nan KJ, Song TS, Huang C (2009). "MicroRNA profiling of human gastric cancer". Molecular Medicine Reports. 2 (6): 963–70. doi:10.3892/mmr_00000199. PMID 21475928.
• Takahashi Y, Forrest AR, Maeno E, Hashimoto T, Daub CO, Yasuda J (August 2009). Blagosklonny MV (ed.). "MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines". PLOS ONE. 4 (8): e6677. doi:10.1371/journal.pone.0006677. PMC 2722734. PMID 19688090.
• Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P, Sevignani C, Byrne D, Negrini M, Pagano F, Gomella LG, Croce CM, Baffa R (2007). "Micro-RNA profiling in kidney and bladder cancers". Urologic Oncology. 25 (5): 387–92. doi:10.1016/j.urolonc.2007.01.019. PMID 17826655.
• Choong ML, Yang HH, McNiece I (April 2007). "MicroRNA expression profiling during human cord blood-derived CD34 cell erythropoiesis". Experimental Hematology. 35 (4): 551–64. doi:10.1016/j.exphem.2006.12.002. PMID 17379065.

External links

• Page for mir-185 microRNA precursor family at Rfam

• Rfam pages needing a picture
• MicroRNA
• MicroRNA precursor families