The Holin superfamily VI is a superfamily of integral membrane transport proteins. It is one of the seven different holin superfamilies in total. In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families and individual members.
The Holin superfamily VI includes two TC families:
Superfamily VI includes families with members only from Bacillota. These proteins appear to have one N-terminal transmembrane segment (TMS), followed by an amphipathic, weakly hydrophobic peak that was not predicted to be transmembrane by the topological programs used by Reddy and Saier (2013). The average sizes of the members of the two families belonging to the Holin superfamily VI are 135 ± 11 and 130 ± 26 amino acyl residues (aas), respectively.
See also
References
- "Holin Superfamily VI". Transporter Classification Database. Retrieved 2016-03-20.
- ^ Reddy, Bhaskara L.; Saier Jr., Milton H. (2013-11-01). "Topological and phylogenetic analyses of bacterial holin families and superfamilies". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828 (11): 2654–2671. doi:10.1016/j.bbamem.2013.07.004. PMC 3788059. PMID 23856191.
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