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Divaplon

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Revision as of 22:28, 18 September 2011 by BogBot (talk | contribs) (populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Divaplon
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • (6-ethyl-7-methoxy-5-methylimidazopyrimidin-2-yl)-phenylmethanone
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H17N3O2
Molar mass295.336 g·mol
3D model (JSmol)
SMILES
  • CCC1=C(N2C=C(N=C2N=C1OC)C(=O)C3=CC=CC=C3)C
  (what is this?)  (verify)

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the pyrazolopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABAA receptor in the brain.

References

  1. Feely, M; Boyland, P; Picardo, A; Cox, A; Gent, JP (1989). "Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812". European journal of pharmacology. 164 (2): 377–80. doi:10.1016/0014-2999(89)90482-2. PMID 2759183.
  2. Sanger, DJ; Joly, D; Perrault, G (1995). "Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice". Psychopharmacology. 121 (1): 104–8. PMID 8539334.
  3. Pellón, R; Ruíz, A; Lamas, E; Rodríguez, C (2007). "Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats". Behavioural pharmacology. 18 (1): 81–7. doi:10.1097/FBP.0b013e3280143212. PMID 17218801.
Anxiolytics (N05B)
5-HT1ARTooltip 5-HT1A receptor agonists
GABAARTooltip GABAA receptor PAMsTooltip positive allosteric modulators
Hypnotics
Gabapentinoids
(α2δ VDCC blockers)
Antidepressants
Antipsychotics
Sympatholytics
(Antiadrenergics)
Others
Categories:
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