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Revision as of 13:47, 26 February 2023 editJWBE (talk | contribs)Extended confirmed users10,129 editsm (GR) File renamed: File:Thymidine monophosphate anion 3D spacefill.png → File:Deoxythymidine monophosphate anion 3D spacefill.png← Previous edit Latest revision as of 02:08, 22 August 2023 edit undo132.183.13.29 (talk)No edit summary 
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|Section2={{Chembox Properties |Section2={{Chembox Properties
| Formula = C<sub>10</sub>H<sub>14</sub>N<sub>2</sub>O<sub>8</sub>P<sup>1−</sup> | Formula = C<sub>10</sub>H<sub>15</sub>N<sub>2</sub>O<sub>8</sub>P
| MolarMass = 321.2005 g mol<sup>−1</sup> | MolarMass = 322.2085 g mol<sup>−1</sup>
}} }}
}} }}

Latest revision as of 02:08, 22 August 2023

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Thymidine monophosphate
Skeletal formula of thymidine monophosphate as an anion, single negative charge
Space-filling model of the thymidine monophosphate molecule as an anion, double negative charge
Names
IUPAC name Thymidine monophosphate
Other names 5'-Thymidylic acid
Identifiers
CAS Number
3D model (JSmol)
Abbreviations dTMP
Beilstein Reference 3916216
ChEBI
ChEMBL
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/p-2Key: GYOZYWVXFNDGLU-UHFFFAOYSA-L
SMILES
  • CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)O)O
Properties
Chemical formula C10H15N2O8P
Molar mass 322.2085 g mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. dTMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine monophosphate often does not contain the "deoxy" prefix in its name; nevertheless, its symbol often includes a "d" ("dTMP"). Dorland’s Illustrated Medical Dictionary provides an explanation of the nomenclature variation at its entry for thymidine.

As a substituent, it is called by the prefix thymidylyl-.

See also

References

  1. Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
  2. Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.


Nucleic acid constituents
Nucleobase
Nucleoside
Ribonucleoside
Deoxyribonucleoside
Nucleotide
(Nucleoside monophosphate)
Ribonucleotide
Deoxyribonucleotide
Cyclic nucleotide
Nucleoside diphosphate
Nucleoside triphosphate


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